Trends in the morbidity rate of dengue infection among population in Tha Wung District, Lopburi Province, Thailand, 2012-2020

Dengue is a viral infection transmitted by Aedes mosquitoes. It constitutes a significant public health issue in Thailand. Thus, this study aims to determine trends in the morbidity rate of dengue infection and the prevalence and associated factors of thrombocytopenia among dengue patients. Data on dengue cases were retrieved from Tha Wung Hospital electronic medical records based on ICD-10 diagnoses: A90 and A91. Between 2012 and 2020, there were 1260 dengue cases presented to Tha Wung Hospital. Descriptive analysis included characteristics of dengue patients and spatiotemporal patterns of disease. Chi-square for trend was used to determine trends in the morbidity rate of dengue infection. Logistic regression was used to identify associated factors of thrombocytopenia in dengue patients. A total of 1260 dengue patients were included in the study. Trends in the morbidity rate of dengue infection increased significantly from 2012 to 2020. There were 402 patients with thrombocytopenia (31.9%) and 858 patients without thrombocytopenia (68.1%). The risk factors of thrombocytopenia in dengue patients are age greater than or equal to 13 years old in the age group under 20 years and increasing yearly among patients aged 20 years and over. Thus, effective preventive measures and appropriate management protocols according to age should be implemented.